Background: Heart failure is a leading cause for hospital readmission
Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker
In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF)
The most common drugs used to treat heart failure in patients with reduced ejection fraction include a diuretic; an angiotensin system blocker (angiotensin
In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF)
Digoxin use may lower this risk in patients with heart failure with reduced ejection fraction (HFrEF), but data on contemporary patients receiving other evidence-based therapies are lacking
86 The 1,204 matched patients had a mean (±standard deviation) age of 76 (±11) years and left ventricular ejection fraction of 28 (±10) percent; 40% were female, Effects of discontinuation of digoxin versus continuation at low serum digoxin concentrations in chronic heart failure
Digoxin is one of the oldest compounds used in cardiovascular medicine
They found that digoxin use was associated with a significant reduction in the risk of heart failure readmission at 30 days, 1 year and 6 years (HR: 0
The normal range is 63-77% for males and 55-75% for females
People with heart failure associated with preserved left ventricular ejection fraction may experience a decreased cardiac output with digoxin
40% to 49% is mid-range ejection fraction: The heart’s pumping ability is slightly below normal
Before matching, patients in the digoxin discontinuation group were older, had higher left ventricular ejection fraction, and fewer of these patients had received GDMT for HFrEF
There are no dose ranging studies with MRAs for clinical efficacy
the use of digitoxin should be preferred in this patient group, since digoxin is excreted primarily via
23 Current American Heart Association/American College of Cardiology guidelines classify digoxin use as IIA in
Adding digoxin, low-dose amiodarone, or other rhythm and/or rate controlling Background: The deleterious effects of discontinuation of digoxin on outcomes in ambulatory patients with chronic heart failure (HF) with reduced ejection fraction (HFrEF) receiving angiotensin-converting enzyme inhibitors are well-documented
12 We TSH and/or digoxin level depending on context