4% to 14
Minocycline is a variant of the antibiotic and thus is also prescribed as a treatment for bacterial infections
Treatment of tetracycline and minocycline induced staining can be treated with bleaching, composite or porcelain veneers, or crowns, but these methods are Minocycline is a broad-spectrum antibiotic belonging to the tetracycline family, often prescribed in infective skin conditions such as acne and rosacea
I have also managed a patient with the condition of minocycline-induced Staining of the adult dentition appears to occur in 3-6% of patients taking long‐term minocycline at > 100 mg daily
The prevalence of tetracycline and minocycline staining is 3-6%
gingival tissues, as reported in some cases
Minocycline seldom causes significant adverse ef fects; however, it has been associated with intracranial hypertension, gastrointestinal toxicity, nephritis, and hepatitis
8 In type 3, changes are nonspecific, consisting of increased However, minocycline, a tetracycline derivative, has been reported to stain adult dentition in 3-6% of patients taking a daily dose >100 mg for longer than 1 month
MIP may resolve following discontinuation of minocycline therapy or it may persist indefinitely
Tetracycline stains bone a fluorescent yellow and minocycline, more commonly used for chronic acne, stains bone dark green
Minocycline staining of the oral cavity J Am Acad Dermatol
Affiliation 1 Minocycline is a broad-spectrum antibiotic belonging to the tetracycline family, often prescribed in infective skin conditions such as acne and rosacea
Minocycline staining Br Dent J
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These changes are the result of an oxidation product of tetracycline induced by exposure to light
Tetracycline and Its Derivatives
Other antibiotics in the tetracycline family, such as doxycycline and minocycline, have similar uses
Tetracycline treatment in young children during the rapid calcification phase of teeth results in staining of permanent teeth, first described in 1959
Your article states " Can tetracycline or minocycline tooth stains be prevented or treated? The overall prevalence of tetracycline induced staining has been reported to be 3-4% and 3-6% for minocycline
Treatment planning for severely tetracycline-stained teeth usually involves placement of veneers or crowns to cover the darkened teeth
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Authors Vikki L Noonan 1 , Sadru Kabani, James Wu
Results: No treatment was rendered since the patient was not concerned with the A 25-year-old woman with gray striated staining on all teeth took minocycline for two years
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In addition, a fine, granular pigmentation that stained black was also observed with Fontana-Masson staining (Fig
Staining of the teeth, oral mucosa, sclerae and ears: case report
Based on the few studies available, this kind of hyperpigmentation occurs in 2
Unfortunately this fall right in the middle of common acne treatment dosages, which are 100 to 200 mg/day 100 mg twice daily for 5 days, minocycline treatment is usually followed by administration of rifampicin
Br Dent J, 215(2):71-73, 01 Jul 2013 Cited by: 6 articles | PMID: 23887527
The discoloration varies from blue, slate-gray, or brown, and it typically occurs in a dose-dependent fashion These stains showed the presence of hemosiderin, a typical finding arising from old hemorrhage
It is believed that minocycline binds to the tooth and then oxidizes it, producing a discoloration
UNLABELLED It has been well acknowledged in recent literature that minocycline, a semisynthetic tetracycline derivative, causes discolorations in adult teeth and Minocycline hydrochloride use has been associated with various forms of hyperpigmentation, and its incidence is well reported in acne vulgaris and rheumatoid arthritis
Discoloration of oral mucus This case is unusual in that the tooth discoloration disappeared after discontinuing minocycline therapy, and clinicians need to be aware of this adverse drug reaction, as this agent may be used increasingly in the treatment of adults with arthritis
Minocycline differs from other tetracyclines in that it is well absorbed from the gastrointestinal tract and chelates with iron to form insoluble complexes, and this may provoke the tooth staining
Minocycline-induced staining of the sclerae, ears, gingivae
5 Altmetric Metrics Sir, I was very pleased to read Dr Johnston's paper Feeling blue? Minocycline-induced staining of the teeth, oral mucosa, sclerae and ears
The remarkable side-effect of minocycline on the oral cavity is the singular occurrence of “black bones”, “black or green roots” and blue-gray to gray hue darkening
D
; MARK BE N TEIN, D
A case of staining to only the crowns of unerupted third molars in a girl prescribed minocycline at age 16 for papulopustular acne is reported, highlighting current
doi: 10
Three types of minocycline-induced hyperpigmentation occur 3, 8 : Type 1—blue-grey coloration on the face in areas of inflammation Type 2—blue-grey
But if you have tetracycline
2013
Tooth staining/discoloration with tetracycline is influenced by the dosage used, length of treatment or exposure Minocycline belongs to the tetracycline class of antibiotics and is used to manage and treat both infectious and non-infectious conditions
Four individual cases of oral minocycline-induced scleral pigmentation are re ported in the dermatologic literature
Tetracycline and Its Derivatives
Prevention of staining of teeth can be done by reducing the dose of the drug, avoiding the drug in the critical period of mineralization of teeth
The mechanism of minocycline staining is still unknown
A systematic review according to PRISMA guidelines was
This article reports a case of staining to only the crowns of unerupted third molars in a girl prescribed minocycline at age 16 for papulopustular acne
1,2 This adverse drug reaction can obviously create psychological and esthetic concerns for the patient and should be taken into consideration
Tetracycline is an antibiotic to treat several gram-negative and gram-positive infections
Minocycline-induced staining of the adult permanent dentition: a review of the literature and report of a case Dent Update
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This activity reviews the indications, action, and contraindications for tetracyclines as a valuable
2009 Winter;57(4):42
Methods: A case is presented involving a patient with minocycline-induced staining of the torus palatinus and alveolar bone
These finely granular pigments also stained positive with iron stain, indicating the pigment as minocycline-related type 2 The prevalence of tetracycline and minocycline staining is 3-6%
The ability of tetracycline to intrinsically stain teeth during Minocycline staining is characterized by a blue-gray to odontogenesis has been well-known for almost five decades